FERSHT, A. R. : rechercher sur Z-Library

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1

Protein engineering

Leatherbarrow, Robin J., Fersht, Alan R.

Journal:

Protein Engineering Design and Selection

Année:

1986

Langue:

english

Fichier:

PDF, 1.01 MB

english, 1986

2

Awakening guardian angels: drugging the p53 pathway

Brown, Christopher J., Lain, Sonia, Verma, Chandra S., Fersht, Alan R., Lane, David P.

Journal:

Nature Reviews Cancer

Année:

2009

Langue:

english

Fichier:

PDF, 565 KB

english, 2009

3

Redesigning enzyme structure by site-directed mutagenesis: tyrosyl tRNA synthetase and ATP binding

Winter, Greg, Fersht, Alan R., Wilkinson, Anthony J., Zoller, Mark, Smith, Michael

Journal:

Année:

1982

Fichier:

PDF, 448 KB

1982

4

Folding & Design: introduction to a new journal

Alan R. Fersht, Fred E. Cohen

Journal:

Folding and Design

Année:

1996

Langue:

english

Fichier:

PDF, 25 KB

english, 1996

5

Strength and co-operativity of contributions of surface salt bridges to protein stability

Amnon Horovitz, Luis Serrano, Boaz Avron, Mark Bycroft, Alan R. Fersht

Journal:

Journal of Molecular Biology

Année:

1990

Langue:

english

Fichier:

PDF, 1.89 MB

english, 1990

6

Hydrolysis of aspirin. Intramolecular general base catalysis of ester hydrolysis

Fersht, A. R., Kirby, Anthony J.

Journal:

Journal of the American Chemical Society

Année:

1967

Langue:

english

Fichier:

PDF, 862 KB

english, 1967

7

Interaction of barnase with its polypeptide inhibitor barstar studied by protein engineering

Schreiber, Gideon, Fersht, Alan R.

Journal:

Année:

1993

Langue:

english

Fichier:

PDF, 1.17 MB

english, 1993

8

The p53 Pathway: Origins, Inactivation in Cancer, and Emerging Therapeutic Approaches

Joerger, Andreas C., Fersht, Alan R.

Journal:

Annual Review of Biochemistry

Année:

2016

Langue:

english

Fichier:

PDF, 3.07 MB

english, 2016

9

A large increase in enzyme–substrate affinity by protein engineering

Wilkinson, Anthony J., Fersht, Alan R., Blow, D. M., Carter, Paul, Winter, Greg

Journal:

Année:

1984

Fichier:

PDF, 294 KB

1984

10

Hydrogen bonding in enzymatic catalysis analysed by protein engineering

Wells, Tim N. C., Fersht, Alan R.

Journal:

Année:

1985

Fichier:

PDF, 202 KB

1985

11

RESCUING THE FUNCTION OF MUTANT p53

Bullock, Alex N., Fersht, Alan R.

Journal:

Nature Reviews Cancer

Année:

2001

Langue:

english

Fichier:

PDF, 1.88 MB

english, 2001

12

Opinion: The present view of the mechanism of protein folding

Daggett, Valerie, Fersht, Alan

Journal:

Nature Reviews Molecular Cell Biology

Année:

2003

Langue:

english

Fichier:

PDF, 610 KB

english, 2003

13

Molecular basis of S100 proteins interacting with the p53 homologs p63 and p73

van Dieck, J, Brandt, T, Teufel, D P, Veprintsev, D B, Joerger, A C, Fersht, A R

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 1020 KB

english, 2010

14

Is there a unifying mechanism for protein folding?

Valerie Daggett, Alan R. Fersht

Journal:

Trends in Biochemical Sciences

Année:

2003

Langue:

english

Fichier:

PDF, 825 KB

english, 2003

15

Stability and function: two constraints in the evolution of barstar and other proteins

Gideon Schreiber, Ashley M Buckle, Alan R Fersht

Journal:

Année:

1994

Langue:

english

Fichier:

PDF, 831 KB

english, 1994

16

Crystal Structural Analysis of Mutations in the Hydrophobic Cores of Barnase

Ashley M. Buckle, Kirn Henrick, Alan R. Fersht

Journal:

Journal of Molecular Biology

Année:

1993

Fichier:

PDF, 862 KB

1993

17

Effect of active site residues in barnase on activity and stability

Elizabeth M. Meiering, Luis Serrano, Alan R. Fersht

Journal:

Journal of Molecular Biology

Année:

1992

Langue:

english

Fichier:

PDF, 1.10 MB

english, 1992

18

Energetics of protein-protein interactions: Analysis ofthe Barnase-Barstar interface by single mutations and double mutant cycles

Gideon Schreiber, Alan R. Fersht

Journal:

Journal of Molecular Biology

Année:

1995

Langue:

english

Fichier:

PDF, 2.57 MB

english, 1995

19

Protein engineering and the study of structure—function relationships in receptors

Walter H.J. Ward, David Timms, Alan R. Fersht

Journal:

Trends in Pharmacological Sciences

Année:

1990

Langue:

english

Fichier:

PDF, 778 KB

english, 1990

20

Structural Biology of the Tumor Suppressor p53

Joerger, Andreas C., Fersht, Alan R.

Journal:

Annual Review of Biochemistry

Année:

2008

Langue:

english

Fichier:

PDF, 1.26 MB

english, 2008

21

The use of double mutants to detect structural changes in the active site of the tyrosyl-tRNA synthetase (Bacillus stearothermophilus)

Carter, Paul J., Winter, Greg, Wilkinson, Anthony J., Fersht, Alan R.

Journal:

Année:

1984

Langue:

english

Fichier:

PDF, 692 KB

english, 1984

22

Engineering of tyrosyl tRNA synthetase

BEDOUELLE, H, CARTER, P, WAYE, M, WINTER, G, LOWE, D, WILKINSON, A, FERSHT, A

Journal:

Année:

1985

Langue:

english

Fichier:

PDF, 527 KB

english, 1985

23

Meningioma Causing Visual Impairment: Outcomes and Toxicity After Intensity Modulated Radiation Therapy

Maclean, Jillian, Fersht, Naomi, Bremner, Fion, Stacey, Chris, Sivabalasingham, Suganya, Short, Susan

Journal:

International Journal of Radiation Oncology*Biology*Physics

Année:

2013

Langue:

english

Fichier:

PDF, 342 KB

english, 2013

24

The Solution Structure of Oxidized Escherichia coli Cytochrome b 562†,‡

Arnesano, Fabio, Banci, Lucia, Bertini, Ivano, Faraone-Mennella, Jasmin, Rosato, Antonio, Barker, Paul D., Fersht, Alan R.

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 261 KB

english, 1999

25

Ligand binding and enzymic catalysis coupled through subunits in tyrosyl-tRNA synthetase

Fersht, Alan R., Mulvey, Roderick S., Koch, Gorden L. E.

Journal:

Année:

1975

Langue:

english

Fichier:

PDF, 1.77 MB

english, 1975

26

Formation of Short-Lived Protein Aggregates Directly from the Coil in Two-State Folding †

Silow, Maria, Tan, Yee-Joo, Fersht, Alan R., Oliveberg, Mikael

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 130 KB

english, 1999

27

Tyrosyl-tRNA synthetase acts as an asymmetric dimer in charging tRNA. A rationale for half-of-the sites activity

Ward, Walter H. J., Fersht, Alan R.

Journal:

Année:

1988

Langue:

english

Fichier:

PDF, 779 KB

english, 1988

28

Reaction of modified and unmodified tRNATyr substrates with tyrosyl-tRNA synthetase (Bacillus stearothermophilus)

Avis, Johanna M., Day, Anthony G., Garcia, George A., Fersht, Alan R.

Journal:

Année:

1993

Langue:

english

Fichier:

PDF, 1.11 MB

english, 1993

29

Introducing Food Fraud including translation and interpretation to Russian, Korean, and Chinese languages

Spink, John, Moyer, Douglas C., Park, Hyeonho, Wu, Yongning, Fersht, Victor, Shao, Bing, Hong, Miao, Paek, Seung Yeop, Edelev, Dmitry

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 413 KB

english, 2015

30

Extrapolation to water of kinetic and equilibrium data for the unfolding of barnase in urea solutions

Matouschek, Andreas, Matthews, Jacqueline M., Johnson, Christopher M., Fersht, Alan R.

Journal:

Protein Engineering Design and Selection

Année:

1994

Langue:

english

Fichier:

PDF, 2.35 MB

english, 1994

31

Contribution of a proline residue and a salt bridge to the stability of a type I reverse turn in chymotrypsin inhibitor-2

de Gay, Gonzalo Prat, Johnson, Christopher M., Fersht, Alan R.

Journal:

Protein Engineering Design and Selection

Année:

1994

Langue:

english

Fichier:

PDF, 2.14 MB

english, 1994

32

In vivo protein stabilization based on fragment complementation and a split GFP system

Stina Lindman, Armando Hernandez-Garcia, Olga Szczepankiewicz, Birgitta Frohm, Sara Linse and Alan R. Fersht

Journal:

Proceedings of the National Academy of Sciences

Année:

2010

Langue:

english

Fichier:

PDF, 1.33 MB

english, 2010

33

Harnessing fluorine-sulfur contacts and multipolar interactions for the design of p53 mutant Y220C rescue drugs

Bauer, Matthias R., Jones, Rhiannon N., Baud, Matthias G. J., Wilcken, Rainer, Boeckler, Frank M., Fersht, Alan R, Joerger, Andreas C., Spencer, John

Journal:

ACS Chemical Biology

Année:

2016

Langue:

english

Fichier:

PDF, 9.49 MB

english, 2016

34

Structure and Function of Intrinsically Disordered Proteins || Principles of Protein Structure and Function

Tompa, Peter, Fersht, Alan

Année:

2009

Langue:

english

Fichier:

PDF, 821 KB

english, 2009

35

The Enzymes of Glycolysis: Structure, Activity and Evolution || Introductory Remarks to the Third Session

Journal:

Philosophical Transactions of the Royal Society of London Series B Biological Sciences (1934-1990)

Année:

1981

Langue:

english

Fichier:

PDF, 198 KB

english, 1981

36

Structure and Function of Intrinsically Disordered Proteins || Nuclear Magnetic Resonance

Tompa, Peter, Fersht, Alan

Année:

2009

Langue:

english

Fichier:

PDF, 579 KB

english, 2009

37

Structure and Function of Intrinsically Disordered Proteins || Extension of the Structure-Function Paradigm

Tompa, Peter, Fersht, Alan

Année:

2009

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2009

38

Structure and Function of Intrinsically Disordered Proteins || Evolution and Prevalence of Disorder

Tompa, Peter, Fersht, Alan

Année:

2009

Langue:

english

Fichier:

PDF, 642 KB

english, 2009

39

Structure and Function of Intrinsically Disordered Proteins || Spectroscopic Techniques for Characterizing Disorder

Tompa, Peter, Fersht, Alan

Année:

2009

Langue:

english

Fichier:

PDF, 804 KB

english, 2009

40

Structure and Function of Intrinsically Disordered Proteins || Biological Processes Enriched in Disorder

Tompa, Peter, Fersht, Alan

Année:

2009

Langue:

english

Fichier:

PDF, 841 KB

english, 2009

41

Structure and Function of Intrinsically Disordered Proteins || Prediction of Disorder

Tompa, Peter, Fersht, Alan

Année:

2009

Langue:

english

Fichier:

PDF, 686 KB

english, 2009

42

Structure and Function of Intrinsically Disordered Proteins || A Brief History of Protein Disorder

Tompa, Peter, Fersht, Alan

Année:

2009

Langue:

english

Fichier:

PDF, 323 KB

english, 2009

43

Structure and Function of Intrinsically Disordered Proteins || References

Tompa, Peter, Fersht, Alan

Année:

2009

Langue:

english

Fichier:

PDF, 1.40 MB

english, 2009

44

Structure and Function of Intrinsically Disordered Proteins || Proteomic Approaches for the Identification of IDPs

Tompa, Peter, Fersht, Alan

Année:

2009

Langue:

english

Fichier:

PDF, 257 KB

english, 2009

45

Structure and Function of Intrinsically Disordered Proteins || Indirect Techniques for Recognizing and Characterizing Protein Disorder

Tompa, Peter, Fersht, Alan

Année:

2009

Langue:

english

Fichier:

PDF, 442 KB

english, 2009

46

Structure and Function of Intrinsically Disordered Proteins || Structure of IDPs

Tompa, Peter, Fersht, Alan

Année:

2009

Langue:

english

Fichier:

PDF, 787 KB

english, 2009

47

Structure and Function of Intrinsically Disordered Proteins || Structural Disorder and Disease

Tompa, Peter, Fersht, Alan

Année:

2009

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2009

48

Structure and Function of Intrinsically Disordered Proteins || IDPs under Conditions Approaching In Vivo

Tompa, Peter, Fersht, Alan

Année:

2009

Langue:

english

Fichier:

PDF, 532 KB

english, 2009

49

Structure and Function of Intrinsically Disordered Proteins || Molecular Functions of Disordered Proteins

Tompa, Peter, Fersht, Alan

Année:

2009

Langue:

english

Fichier:

PDF, 992 KB

english, 2009

50

Structure and Function of Intrinsically Disordered Proteins || Hydrodynamic Techniques

Tompa, Peter, Fersht, Alan

Année:

2009

Langue:

english

Fichier:

PDF, 580 KB

english, 2009